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更新于 5月27日

轉(zhuǎn)化科學資深科學家

面議
  • 南京江寧區(qū)
  • 經(jīng)驗不限
  • 博士
  • 全職
  • 招1人

職位描述

細胞培養(yǎng)技術(shù)生物藥
Key Responsibilities: ?Lead the design, development, and optimization of translational (e.g. ex vivo) assays to evaluate the clinical profile of cell therapy candidates. ?Contribute to translational strategies of novel gene and therapy products. ?Act as a subject matter expert (SME) in translational assays, such as ex vivo assays, collaborate with cross-functional teams, including research, preclinical, clinical, and bioanalytics, to ensure comprehensive translational assessments. ?Provide scientific leadership in CAR-T and patient sample-related immune cell isolation, culture, and differentiation techniques to ensure the generation of high-quality, reproducible and clinically relevant ex vivo models. ?Develop novel assay platforms to evaluate and address key translational questions therapeutic candidates, utilize advanced technologies (e.g. flow cytometry, immune assays, etc.) for translational characterization and deep dive. ?Analyze and interpret data, communicate findings through reports and presentations. ?Maintain up-to-date knowledge of innovative CAR-T and gene therapy competitive landscape and evaluation methods to drive translational efforts. ?Ensure project timelines, deliverables, and budgets are met, while continuously improving assay design, throughput, reliability and clinical relevance. Qualifications: ?Ph.D. in Immunology, Cell Biology, or a related field with 1-5 years of relevant experience within the cell therapy or related biotech/pharmaceutical industry. ?Extensive experience with in vitro assays for assessing cell therapy safety, efficacy, MOA and other related attributes. ?Proven expertise in immune cell culture, such as (CAR-engineered) T cells, NK cells, or macrophages is required. ?Proficiency in a variety of assay techniques such as flow cytometry, ELISA, PCR and immunofluorescence. ?In-depth understanding of cell therapy platforms, such as CAR-T, CAR-NK, or other engineered cellular products is highly desired. Prior experience with in vivo CAR-T or gene therapy is a plus. ?Experience supporting IND applications with preclinical data, experience working in a GxP or GLP-compliant environment will be appreciated. ?Demonstrated ability to lead complex scientific projects and to work in a matrixed, multidisciplinary environment. Demonstrated project management skills to pursue multiple leads and to deliver. ?Demonstrated ability to think critically. ?Excellent communication and presentation skills, with a proven track record of publications and presentations in the field. ?Leadership experience, with the ability to mentor and guide junior scientists and foster a collaborative research environment.

工作地點

江寧區(qū)南京同方科技園有限公司

職位發(fā)布者

相美玲/招聘小姐姐

立即溝通
公司Logo南京傳奇生物科技有限公司
關(guān)于傳奇生物傳奇生物(NASDAQ: LEGN)是一家處于臨床階段的全球生物制藥公司,成立于2014年,并于美國時間2020年6月5日在納斯達克掛牌上市,成為國內(nèi)第一家CART療法上市公司。傳奇生物專注于腫瘤和其他領(lǐng)域的新型細胞療法的開發(fā)。目前在全球免疫細胞療法領(lǐng)域位列第一方陣,和合作伙伴Janssen將最領(lǐng)先的產(chǎn)品LCAR-B38M細胞制劑已推進至在美國、歐洲藥品上市審評階段,有望解決多發(fā)性骨髓瘤治療的世界級難題。與此同時,傳奇生物還有多款在研CAR-T療法,用于血液瘤、實體瘤及其它疑難疾病的治療。目前,傳奇生物在美國、中國和歐洲已擁有1000余名員工,以差異化技術(shù)、全球化研發(fā)網(wǎng)絡(luò)和專業(yè)的生產(chǎn)策略為有力支撐,為患者提供發(fā)現(xiàn)、開發(fā)和制造一流的細胞療法創(chuàng)造了可能。公司已入選江蘇省戰(zhàn)略性新興產(chǎn)業(yè)發(fā)展專項資金項目,江蘇省精準細胞免疫治療工程技術(shù)研究中心,榮獲江蘇省科技進步獎、“中國生物醫(yī)藥產(chǎn)業(yè)鏈創(chuàng)新風云榜”并獲“鯤鵬獎”,入選“2020中國獨角獸”、“中國醫(yī)藥創(chuàng)新企業(yè)100強”。
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